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Restylane Refyne and Defyne

We are the first in the Triad with these next-generation fillers!

Flexible new fillers target moderate to severe smile and laugh lines while maintaining natural expression

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Learn more about Restylane Refyne for moderate smile and laugh lines

Learn more about Restylane Defyne for deep smile and laugh lines

Galderma, the maker of injectables like Restylane, Sculptra, and Dysport, now has two new FDA approved fillers: Restylane® Refyne and Defyne. Restylane® Refyne was approved to treat moderate wrinkles and folds from the nose to mouth. Restylane® Defyne is approved to plump and fill deep-set lines. Both use next-generation flexible hyaluronic acid gels designed to give you the flexibility to show your natural range of facial expression.

Made with XpresHAn Technology™, NEW Restylane Refyne and NEW Restylane Defyne help offer just the right amount of lift to laugh lines (nasolabial folds and marionette lines) - all while preserving your ability to show your range of natural facial expressions.

Restylane® Refyne and Restylane® Defyne have been shown to maintain effectiveness for the treatment of laugh lines for up to 12 months.

Restylane® Refyne for moderate smile and laugh lines

A next-generation hyaluronic acid dermal filler designed to help support your skin while keeping you looking like you. NEW Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions. So, you always look like you. As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) appear more noticeable. Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn Technology™ that helps correct these lines for a more natural look to your face. The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression - for real-life results that help maintain natural movement when you're smiling, frowning and even puckering up.

Restylane® Defyne for for deep smile and laugh lines

Crafted with XpresHAn Technology™, NEW Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions. As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) become more pronounced. Restylane Defyne is crafted with XpresHAn Technology™ to correct these deepened lines. The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions - for natural-looking results that help maintain your natural movement.

Who Performs Restylane® Refyne and Defyne Injections?

Laugh line injections are an art and require great finesse to achieve the best results and a natural look. At Carolina Laser and Cosmetic Center, only Dr. Anne White injects dermal fillers, NOT A PA OR A NURSE.

Our patients appreciate that they have a top-trained and experienced Cosmetic Surgeon injecting them in order to produce the best results possible. Using her keen eye for detail and her passion for artistry, Dr. White expertly injects her patients' lips, producing top results every time. She is known as a leader in injection techniques. Companies such as Allergan and Galderma, which manufacture and distribute injectable fillers to cosmetic clinics in the United States, regularly request that Dr. White provide progress and development training for other medical professionals.


Join the ASPIRE Galderma Rewards Program for great savings and rewards for Dysport®, Restylane®,, Restylane® Lift, Restylane® Silk, Restylane Refyne and Defyne and Sculptra Aesthetic.

Restylane Refyne and Defyne Wrinkle Filler Fillers Winston-Salem NC Winston Salem North Carolina



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